diff --git a/packages/vite/src/node/server/middlewares/static.ts b/packages/vite/src/node/server/middlewares/static.ts
index 4ffd4e000dd42b..7672cb8506d0b9 100644
--- a/packages/vite/src/node/server/middlewares/static.ts
+++ b/packages/vite/src/node/server/middlewares/static.ts
@@ -78,7 +78,7 @@ export function serveStaticMiddleware(
       return next()
     }
 
-    const url = new URL(req.url!, 'http://example.com')
+    const url = new URL(req.url!.replace(/^\/+/, '/'), 'http://example.com')
     const pathname = decodeURIComponent(url.pathname)
 
     // apply aliases to static requests as well
@@ -125,7 +125,7 @@ export function serveRawFsMiddleware(
 
   // Keep the named function. The name is visible in debug logs via `DEBUG=connect:dispatcher ...`
   return function viteServeRawFsMiddleware(req, res, next) {
-    const url = new URL(req.url!, 'http://example.com')
+    const url = new URL(req.url!.replace(/^\/+/, '/'), 'http://example.com')
     // In some cases (e.g. linked monorepos) files outside of root will
     // reference assets that are also out of served root. In such cases
     // the paths are rewritten to `/@fs/` prefixed paths and must be served by