diff --git a/sentry_sdk/integrations/aiohttp.py b/sentry_sdk/integrations/aiohttp.py
index 8b6c783530..e412fd931d 100644
--- a/sentry_sdk/integrations/aiohttp.py
+++ b/sentry_sdk/integrations/aiohttp.py
@@ -15,6 +15,7 @@
 from sentry_sdk.utils import (
     capture_internal_exceptions,
     event_from_exception,
+    parse_version,
     transaction_from_function,
     HAS_REAL_CONTEXTVARS,
     CONTEXTVARS_ERROR_MESSAGE,
@@ -64,10 +65,10 @@ def __init__(self, transaction_style="handler_name"):
     def setup_once():
         # type: () -> None
 
-        try:
-            version = tuple(map(int, AIOHTTP_VERSION.split(".")[:2]))
-        except (TypeError, ValueError):
-            raise DidNotEnable("AIOHTTP version unparsable: {}".format(AIOHTTP_VERSION))
+        version = parse_version(AIOHTTP_VERSION)
+
+        if version is None:
+            raise DidNotEnable("Unparsable AIOHTTP version: {}".format(AIOHTTP_VERSION))
 
         if version < (3, 4):
             raise DidNotEnable("AIOHTTP 3.4 or newer required.")
diff --git a/sentry_sdk/integrations/arq.py b/sentry_sdk/integrations/arq.py
index 1a6ba0e7c4..684533b6f9 100644
--- a/sentry_sdk/integrations/arq.py
+++ b/sentry_sdk/integrations/arq.py
@@ -14,6 +14,7 @@
     capture_internal_exceptions,
     event_from_exception,
     SENSITIVE_DATA_SUBSTITUTE,
+    parse_version,
 )
 
 try:
@@ -45,11 +46,15 @@ def setup_once():
 
         try:
             if isinstance(ARQ_VERSION, str):
-                version = tuple(map(int, ARQ_VERSION.split(".")[:2]))
+                version = parse_version(ARQ_VERSION)
             else:
                 version = ARQ_VERSION.version[:2]
+
         except (TypeError, ValueError):
-            raise DidNotEnable("arq version unparsable: {}".format(ARQ_VERSION))
+            version = None
+
+        if version is None:
+            raise DidNotEnable("Unparsable arq version: {}".format(ARQ_VERSION))
 
         if version < (0, 23):
             raise DidNotEnable("arq 0.23 or newer required.")
diff --git a/sentry_sdk/integrations/boto3.py b/sentry_sdk/integrations/boto3.py
index a4eb400666..d8e505b593 100644
--- a/sentry_sdk/integrations/boto3.py
+++ b/sentry_sdk/integrations/boto3.py
@@ -7,7 +7,7 @@
 
 from sentry_sdk._functools import partial
 from sentry_sdk._types import TYPE_CHECKING
-from sentry_sdk.utils import parse_url
+from sentry_sdk.utils import parse_url, parse_version
 
 if TYPE_CHECKING:
     from typing import Any
@@ -30,14 +30,17 @@ class Boto3Integration(Integration):
     @staticmethod
     def setup_once():
         # type: () -> None
-        try:
-            version = tuple(map(int, BOTOCORE_VERSION.split(".")[:3]))
-        except (ValueError, TypeError):
+
+        version = parse_version(BOTOCORE_VERSION)
+
+        if version is None:
             raise DidNotEnable(
                 "Unparsable botocore version: {}".format(BOTOCORE_VERSION)
             )
+
         if version < (1, 12):
             raise DidNotEnable("Botocore 1.12 or newer is required.")
+
         orig_init = BaseClient.__init__
 
         def sentry_patched_init(self, *args, **kwargs):
diff --git a/sentry_sdk/integrations/bottle.py b/sentry_sdk/integrations/bottle.py
index 71c4f127f6..cc6360daa3 100644
--- a/sentry_sdk/integrations/bottle.py
+++ b/sentry_sdk/integrations/bottle.py
@@ -5,6 +5,7 @@
 from sentry_sdk.utils import (
     capture_internal_exceptions,
     event_from_exception,
+    parse_version,
     transaction_from_function,
 )
 from sentry_sdk.integrations import Integration, DidNotEnable
@@ -57,10 +58,10 @@ def __init__(self, transaction_style="endpoint"):
     def setup_once():
         # type: () -> None
 
-        try:
-            version = tuple(map(int, BOTTLE_VERSION.replace("-dev", "").split(".")))
-        except (TypeError, ValueError):
-            raise DidNotEnable("Unparsable Bottle version: {}".format(version))
+        version = parse_version(BOTTLE_VERSION)
+
+        if version is None:
+            raise DidNotEnable("Unparsable Bottle version: {}".format(BOTTLE_VERSION))
 
         if version < (0, 12):
             raise DidNotEnable("Bottle 0.12 or newer required.")
diff --git a/sentry_sdk/integrations/chalice.py b/sentry_sdk/integrations/chalice.py
index 6381850560..25d8b4ac52 100644
--- a/sentry_sdk/integrations/chalice.py
+++ b/sentry_sdk/integrations/chalice.py
@@ -8,6 +8,7 @@
 from sentry_sdk.utils import (
     capture_internal_exceptions,
     event_from_exception,
+    parse_version,
 )
 from sentry_sdk._types import TYPE_CHECKING
 from sentry_sdk._functools import wraps
@@ -102,10 +103,12 @@ class ChaliceIntegration(Integration):
     @staticmethod
     def setup_once():
         # type: () -> None
-        try:
-            version = tuple(map(int, CHALICE_VERSION.split(".")[:3]))
-        except (ValueError, TypeError):
+
+        version = parse_version(CHALICE_VERSION)
+
+        if version is None:
             raise DidNotEnable("Unparsable Chalice version: {}".format(CHALICE_VERSION))
+
         if version < (1, 20):
             old_get_view_function_response = Chalice._get_view_function_response
         else:
diff --git a/sentry_sdk/integrations/falcon.py b/sentry_sdk/integrations/falcon.py
index f4bc361fa7..1bb79428f1 100644
--- a/sentry_sdk/integrations/falcon.py
+++ b/sentry_sdk/integrations/falcon.py
@@ -8,6 +8,7 @@
 from sentry_sdk.utils import (
     capture_internal_exceptions,
     event_from_exception,
+    parse_version,
 )
 
 from sentry_sdk._types import TYPE_CHECKING
@@ -131,9 +132,10 @@ def __init__(self, transaction_style="uri_template"):
     @staticmethod
     def setup_once():
         # type: () -> None
-        try:
-            version = tuple(map(int, FALCON_VERSION.split(".")))
-        except (ValueError, TypeError):
+
+        version = parse_version(FALCON_VERSION)
+
+        if version is None:
             raise DidNotEnable("Unparsable Falcon version: {}".format(FALCON_VERSION))
 
         if version < (1, 4):
diff --git a/sentry_sdk/integrations/flask.py b/sentry_sdk/integrations/flask.py
index ea5a3c081a..47e96edd3c 100644
--- a/sentry_sdk/integrations/flask.py
+++ b/sentry_sdk/integrations/flask.py
@@ -10,6 +10,7 @@
 from sentry_sdk.utils import (
     capture_internal_exceptions,
     event_from_exception,
+    parse_version,
 )
 
 if TYPE_CHECKING:
@@ -64,16 +65,13 @@ def __init__(self, transaction_style="endpoint"):
     def setup_once():
         # type: () -> None
 
-        # This version parsing is absolutely naive but the alternative is to
-        # import pkg_resources which slows down the SDK a lot.
-        try:
-            version = tuple(map(int, FLASK_VERSION.split(".")[:3]))
-        except (ValueError, TypeError):
-            # It's probably a release candidate, we assume it's fine.
-            pass
-        else:
-            if version < (0, 10):
-                raise DidNotEnable("Flask 0.10 or newer is required.")
+        version = parse_version(FLASK_VERSION)
+
+        if version is None:
+            raise DidNotEnable("Unparsable Flask version: {}".format(FLASK_VERSION))
+
+        if version < (0, 10):
+            raise DidNotEnable("Flask 0.10 or newer is required.")
 
         before_render_template.connect(_add_sentry_trace)
         request_started.connect(_request_started)
diff --git a/sentry_sdk/integrations/rq.py b/sentry_sdk/integrations/rq.py
index 2696cbff3c..f3cff154bf 100644
--- a/sentry_sdk/integrations/rq.py
+++ b/sentry_sdk/integrations/rq.py
@@ -11,6 +11,7 @@
     capture_internal_exceptions,
     event_from_exception,
     format_timestamp,
+    parse_version,
 )
 
 try:
@@ -39,9 +40,9 @@ class RqIntegration(Integration):
     def setup_once():
         # type: () -> None
 
-        try:
-            version = tuple(map(int, RQ_VERSION.split(".")[:3]))
-        except (ValueError, TypeError):
+        version = parse_version(RQ_VERSION)
+
+        if version is None:
             raise DidNotEnable("Unparsable RQ version: {}".format(RQ_VERSION))
 
         if version < (0, 6):
diff --git a/sentry_sdk/integrations/sanic.py b/sentry_sdk/integrations/sanic.py
index e6838ab9b0..f9474d6bb6 100644
--- a/sentry_sdk/integrations/sanic.py
+++ b/sentry_sdk/integrations/sanic.py
@@ -10,6 +10,7 @@
     event_from_exception,
     HAS_REAL_CONTEXTVARS,
     CONTEXTVARS_ERROR_MESSAGE,
+    parse_version,
 )
 from sentry_sdk.integrations import Integration, DidNotEnable
 from sentry_sdk.integrations._wsgi_common import RequestExtractor, _filter_headers
@@ -51,15 +52,15 @@
 
 class SanicIntegration(Integration):
     identifier = "sanic"
-    version = (0, 0)  # type: Tuple[int, ...]
+    version = None
 
     @staticmethod
     def setup_once():
         # type: () -> None
 
-        try:
-            SanicIntegration.version = tuple(map(int, SANIC_VERSION.split(".")))
-        except (TypeError, ValueError):
+        SanicIntegration.version = parse_version(SANIC_VERSION)
+
+        if SanicIntegration.version is None:
             raise DidNotEnable("Unparsable Sanic version: {}".format(SANIC_VERSION))
 
         if SanicIntegration.version < (0, 8):
@@ -225,7 +226,7 @@ async def sentry_wrapped_error_handler(request, exception):
         finally:
             # As mentioned in previous comment in _startup, this can be removed
             # after https://github.com/sanic-org/sanic/issues/2297 is resolved
-            if SanicIntegration.version == (21, 9):
+            if SanicIntegration.version and SanicIntegration.version == (21, 9):
                 await _hub_exit(request)
 
     return sentry_wrapped_error_handler
diff --git a/sentry_sdk/integrations/sqlalchemy.py b/sentry_sdk/integrations/sqlalchemy.py
index 5c5adec86d..168aca9e04 100644
--- a/sentry_sdk/integrations/sqlalchemy.py
+++ b/sentry_sdk/integrations/sqlalchemy.py
@@ -1,7 +1,5 @@
 from __future__ import absolute_import
 
-import re
-
 from sentry_sdk._compat import text_type
 from sentry_sdk._types import TYPE_CHECKING
 from sentry_sdk.consts import SPANDATA
@@ -9,6 +7,8 @@
 from sentry_sdk.integrations import Integration, DidNotEnable
 from sentry_sdk.tracing_utils import record_sql_queries
 
+from sentry_sdk.utils import parse_version
+
 try:
     from sqlalchemy.engine import Engine  # type: ignore
     from sqlalchemy.event import listen  # type: ignore
@@ -31,11 +31,9 @@ class SqlalchemyIntegration(Integration):
     def setup_once():
         # type: () -> None
 
-        try:
-            version = tuple(
-                map(int, re.split("b|rc", SQLALCHEMY_VERSION)[0].split("."))
-            )
-        except (TypeError, ValueError):
+        version = parse_version(SQLALCHEMY_VERSION)
+
+        if version is None:
             raise DidNotEnable(
                 "Unparsable SQLAlchemy version: {}".format(SQLALCHEMY_VERSION)
             )
diff --git a/sentry_sdk/utils.py b/sentry_sdk/utils.py
index 58f46e2955..fa9ae15be9 100644
--- a/sentry_sdk/utils.py
+++ b/sentry_sdk/utils.py
@@ -1469,6 +1469,58 @@ def match_regex_list(item, regex_list=None, substring_matching=False):
     return False
 
 
+def parse_version(version):
+    # type: (str) -> Optional[Tuple[int, ...]]
+    """
+    Parses a version string into a tuple of integers.
+    This uses the parsing loging from PEP 440:
+    https://peps.python.org/pep-0440/#appendix-b-parsing-version-strings-with-regular-expressions
+    """
+    VERSION_PATTERN = r"""  # noqa: N806
+        v?
+        (?:
+            (?:(?P<epoch>[0-9]+)!)?                           # epoch
+            (?P<release>[0-9]+(?:\.[0-9]+)*)                  # release segment
+            (?P<pre>                                          # pre-release
+                [-_\.]?
+                (?P<pre_l>(a|b|c|rc|alpha|beta|pre|preview))
+                [-_\.]?
+                (?P<pre_n>[0-9]+)?
+            )?
+            (?P<post>                                         # post release
+                (?:-(?P<post_n1>[0-9]+))
+                |
+                (?:
+                    [-_\.]?
+                    (?P<post_l>post|rev|r)
+                    [-_\.]?
+                    (?P<post_n2>[0-9]+)?
+                )
+            )?
+            (?P<dev>                                          # dev release
+                [-_\.]?
+                (?P<dev_l>dev)
+                [-_\.]?
+                (?P<dev_n>[0-9]+)?
+            )?
+        )
+        (?:\+(?P<local>[a-z0-9]+(?:[-_\.][a-z0-9]+)*))?       # local version
+    """
+
+    pattern = re.compile(
+        r"^\s*" + VERSION_PATTERN + r"\s*$",
+        re.VERBOSE | re.IGNORECASE,
+    )
+
+    try:
+        release = pattern.match(version).groupdict()["release"]  # type: ignore
+        release_tuple = tuple(map(int, release.split(".")[:3]))  # type: Tuple[int, ...]
+    except (TypeError, ValueError, AttributeError):
+        return None
+
+    return release_tuple
+
+
 if PY37:
 
     def nanosecond_time():
diff --git a/tests/test_utils.py b/tests/test_utils.py
index ed8c49b56a..53e3025b98 100644
--- a/tests/test_utils.py
+++ b/tests/test_utils.py
@@ -7,6 +7,7 @@
     logger,
     match_regex_list,
     parse_url,
+    parse_version,
     sanitize_url,
     serialize_frame,
 )
@@ -263,3 +264,39 @@ def test_include_source_context_when_serializing_frame(include_source_context):
 )
 def test_match_regex_list(item, regex_list, expected_result):
     assert match_regex_list(item, regex_list) == expected_result
+
+
+@pytest.mark.parametrize(
+    "version,expected_result",
+    [
+        ["3.5.15", (3, 5, 15)],
+        ["2.0.9", (2, 0, 9)],
+        ["2.0.0", (2, 0, 0)],
+        ["0.6.0", (0, 6, 0)],
+        ["2.0.0.post1", (2, 0, 0)],
+        ["2.0.0rc3", (2, 0, 0)],
+        ["2.0.0rc2", (2, 0, 0)],
+        ["2.0.0rc1", (2, 0, 0)],
+        ["2.0.0b4", (2, 0, 0)],
+        ["2.0.0b3", (2, 0, 0)],
+        ["2.0.0b2", (2, 0, 0)],
+        ["2.0.0b1", (2, 0, 0)],
+        ["0.6beta3", (0, 6)],
+        ["0.6beta2", (0, 6)],
+        ["0.6beta1", (0, 6)],
+        ["0.4.2b", (0, 4, 2)],
+        ["0.4.2a", (0, 4, 2)],
+        ["0.0.1", (0, 0, 1)],
+        ["0.0.0", (0, 0, 0)],
+        ["1", (1,)],
+        ["1.0", (1, 0)],
+        ["1.0.0", (1, 0, 0)],
+        [" 1.0.0 ", (1, 0, 0)],
+        ["  1.0.0   ", (1, 0, 0)],
+        ["x1.0.0", None],
+        ["1.0.0x", None],
+        ["x1.0.0x", None],
+    ],
+)
+def test_parse_version(version, expected_result):
+    assert parse_version(version) == expected_result